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Original Article
One case of hereditary spherocytosis with aplastic crisis.
Kee Young Park, Ho Kyung Choi, Jong Jin Seo, Keon Su Rhee, Yong Hun Chung
Clin Exp Pediatr. 1991;34(6):843-848.   Published online June 30, 1991
We experienced one case of hereditiary spherocytosis with aplastic crisis who was 3 year-old female. On admission, there were pallor and fever. Diagnosis was made by pressence of spherocytes in peripheral blood smear, osmotic fragility test, and bone marrow examination. A brief review of related literature was made.
A case of acute lymphoblastic leukemia complicating neuroblastoma in remission.
Dong Woo Son, Bum Soo Park, Jun Jae Kim, Hong Hoe Koo, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1991;34(5):720-729.   Published online May 31, 1991
As childhood cancer survivors are now increasing in number owing to the improvements in diagnosis, staging, and treatment, concerns have been raised regarding the quality of survival of these patients. One of the limitation to quality and length of survival has been the development of second malignant neoplasm (SMN). In Korea, only one case of SMN has been reported. However, one can expect that...
Clinical analysis and prognostic factors in Henoch-Schonlein purpura .
Ha Young Lee, Chong Sung Chung, Kyu Chul Choeh, Byoung Soo Cho, Young Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1991;34(5):682-690.   Published online May 31, 1991
This study was undertaken to evaluate the prognostic factors of recurrence and renal involvement in Henoch-Sch公nlein purpura. Total 110 cases of anaphylactoid purpura below 15 years of age who admitted to Pediatric Departmen of Kyung Hee University for 8 years from January 1st 1979 to December 31st 1986 were analyzed clinically and statistically. The results were obtained as follows. 1) The peak incidence of age was 4...
A case of homocystinuria.
Kang Seo Park, Kyu Sun Choi, Young Tack Jang, Hong Cheul Lee, Chun Hee Lee
Clin Exp Pediatr. 1991;34(4):566-572.   Published online April 30, 1991
Homocystinuria caused by cystathionine B-synthetase deficiency is characterized biochemically by increased concentration of homocystine and methionine, decreased concentration of cystine in plasma and urine. The manifestation of this rare disorder include skeletal abnormalities, a high incidence of thromboembolism, ectopia lentis, and a high frequency of mental retardation. We experienced a case of homocystinuria in a 10-year-old female patient who had mental retarda- tion, ectopia lentis,...
Endoscopic evaluation for gastrointestinal hemorrhage in childhood.
Cheol Ho Chang, Beom Soo Park, Jeong Kee Seo
Clin Exp Pediatr. 1991;34(4):515-524.   Published online April 30, 1991
The diagnosis and management of gastrointestinal tract hemorrhage in infants and children have been changed dramatically over the past decade. Although previous reviews of this subject have suggested that the cause of gastrointestinal tract bleeding may remain obscure in many patients, recent experience indicates that this is now uncommon. This advance is largely a result of the widespread and now routine application of fiberoptic...
Upper gastrointestinal diseases diagnosed by upper gastrointestinal fiberoptic endoscopy in children.
Jong Moon Hwang, Pal Dong Kim, Tae Won Paik, Chin Moo Kang
Clin Exp Pediatr. 1991;34(2):217-222.   Published online February 28, 1991
A clinical analysis was carried out on 83 cases of upper gastrointestinal diseases, diagnosed by fiberoptic endoscopic examination in children, who had visited the department of pediatrics, Keimyung University, Dong San Hospital from January 1980 to June 1987. Following results were obtained: Out of 83 cases, 61 (73.5%) were between 11-15 years of age and the male to female ratio was 3. 6:1. The disease distribution...
Treatment of severe aplastic anemia: comparison between bone marrow transplantation and immunomodulation.
Dae Chul Jeong, Sung Dong Choi, Woo Gun Choi, Hack Ki Kim, Kyong Su Lee, Du Bong Lee
Clin Exp Pediatr. 1991;34(2):172-179.   Published online February 28, 1991
Twenty, six children younger than 15 years with severe aplastic anemia underwent either bone marrow transplantation or immunomodulation therapy (antilymphocyte globulin with cyclosporin A therapy). Six patients who had an HLA-identical sibling donor underwent bone marrow transplantation after conditioning with cyclophosphamide, procarbazine and antilymphocyte globulin. Twenty children who did not have an HLA-identical donor recieved antilymphocyte globulin and cyclosporin A. The results were as follows; 1) Hematologic responses:...
A case of interstitial pulmonary fibrosis.
Hak Won Kim, Ho Joon Im, In Joon Seol, Ha Baik Lee, Hahng Lee, Seok Chol Jeon, Moon Hyang Park
Clin Exp Pediatr. 1991;34(1):107-114.   Published online January 31, 1991
Interstitial pulmonary fibrosis is a rare, diffuse lug disease which has a tendency to destroy the lung architectures by consequent healing with progressively severe fibrosis. We report with a brief review of literature, one case of a 7-year old female with the typical pictures of interstitial pulmonary fibrosis, histologically on open lung biopsy, and clinically presenting with chronic respiratory difficulty but without definite symptoms...
A Case of Virginal Breast Hypertrophy.
S C Hamm, S W Oh, S S Shim, H D Lee, S Y Kim, H J Park, H J Jun, C Y Kim
Clin Exp Pediatr. 1990;33(12):1741-1747.   Published online December 31, 1990
A 12-year-old girl visited due to massive breast enlargement during past 10 months. We evaluated hormonal levels and radiologic studies but could not find the cause and diagnosed as virginal or juvenile breast hypertrophy. Hormonal therapy was not effective. We relieved her physical discom- fort or mental anguish with reduction mammoplasty and report with brief review of related literatur- es.
A Study of Ultrasonographic findings in Children with Gastrointestinal Symptoms.
Dong Lag Choi, Kwang Sup Kim, Jong Wang Kim, Duk Kyu Kim, Kwang Nam Kim, Ki Yang Ryoo, Hyo Keun Lim
Clin Exp Pediatr. 1990;33(11):1548-1556.   Published online November 30, 1990
We analyzed retrospectively the sonographic findings in 162 children who accompanied with gastrointes- tinal symptoms and performed the comparative analysis of the clinico-pathologic findings to sonographic findings from Jan. 1988 to July 1989. The most frequent symptom was abdominal pain (79.6%). The clinical impression prior to ultrasonography were acute appendicitis (34%), mesenteric lymphadenitis (10.4%), hyper- trophic pyloric stenosis (5%) in order. Positive cases in...
Statistical Survey on Pediatric patients admitted to Kwangju Christian Hospital during 5 years.
Song Nyeon Choi, Young Hee Chung, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1990;33(11):1479-1488.   Published online November 30, 1990
We made a statistical survey on the patients admitted to the Department of Pediatrics of Kwangju Christian Hospital during the past 5 years from Jan. 1984 to Dec. 1988 The results were as follows: 1) The pediatric inpatients during the period totaled 16,119, of which 10,020 were male, with the sex ratio being 1.6:1. 2) Pediatric patients amounted to 17.8% of all admission cases of Kwangju Christian...
A Case of Acute Megakaryoblastic Leukemia in infantwith down Syndrome.
Jang Sik Moon, Hae Young Hwang, Sejung Sohn, Hak Soo Lee, Heum Rye Park
Clin Exp Pediatr. 1990;33(10):1441-1446.   Published online October 31, 1990
Acute megakaryoblastic leukemia is an uncommonly recognized disorder that is characterized by rapidly progressive proliferation of atypical megakaryocytes and their precursor cells, and fatal course. Abnormalities in chromosome 21 may have more than relationship to it. The authors report a case of acute megakaryoblastic leukemia in a 17 day-old male patient who was admitted for evaluation of high fever and dyspnea. The infiltration of atypical megakaryocytes...
One Case of Recovery Phase of Aplastic Crisis in Hereditary Spherocytosis with Family History.
Eun Kyung Won, Dong Hyeon Kim, Ho Seung, Chang Hee Choi
Clin Exp Pediatr. 1990;33(10):1434-1440.   Published online October 31, 1990
We experienced a case of hereditary spherocytosis patient who was in a recovery phase of aplastic crisis at the time of presentation. This was a 7 years old boy with complaints of pallor and intermit- tent abdominal pain. Asymptomatic jaundice was also found in the patient's grandfather and two maternal uncles. Patient’s mother had splenectomy due to hereditary spherocytosis. Diagnosis was made by morphology,...
A Case of Acute Interstitial Nephritis Associated with Yersinia Pseudotuberculosis Infection.
Keun Hee Chung, Yoo Mee Kim, Mee Won Kim, Soon Gi Kim, Moon Soo Park, Jin Keun Chang
Clin Exp Pediatr. 1990;33(8):1123-1128.   Published online August 31, 1990
Authors recently experienced a case of acute interstitial nephritis associated with Yersinia pseudotuberculosis infection in 10-8/12 year old boy, who was admitted to prolonged high fever. On 3rd hospital day, puffy face and oliguria were noted. BUN and serum creatinine rose to peak level, 94.1 mg/dl and 10.1 mg/dl, respectively on 7th hospital day. After then renal functions were normal- ized gradually without specific...
Statistical Observation on Neonate.
Hong Ja Kang, Nam Hyuk Joo, Soon Ok Byun, Ji Sub Oh
Clin Exp Pediatr. 1990;33(8):1037-1047.   Published online August 31, 1990
Statistical observation was performed on 11,857 cases of neonates which were seen in the nursery, Pusan, Wallace Memorial Baptist Hospital, during the past 5 years from Jul. 1983 to Jun. 1988. The results were as follows: 1) Among 11,857 neonates, the percentage distribution by birth weight was 6.1% for 2,500 gm or less, 3.7% for 4,001 gm or more and the sex ratio of male...
A Case of Aplastic Anemia Following hepatitis.
Gae Soon Yeo, Doo Kweon Kim, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1990;33(6):864-869.   Published online June 30, 1990
We experienced a case of aplastic anemia following hepatitis in a 4-year-old girl. Pancytopenia was developed during the convalescent period of hepatitis, and it was getting worse, while serial data of liver function test showed improvement. We tried a methylprednisolone pulse therapy, and about 7 months after treatment the CBC findings returned completely normal. She has enjoyed her healthy life during follow-up of over 2...
Transsphenoidal Meningoencephalocele in Association with Hypopituitarism ans Congenital Dysplastic Optic Disc: A Case Report.
Chang Gee Kang, Jung Wan You, Sung Chul Shin, Myung Goo Min, Duk Hi Kim, Jin Guk Kim, Oh Wong Kwon, Tae Sub Chung
Clin Exp Pediatr. 1990;33(6):842-847.   Published online June 30, 1990
Transsphenoidal meningoencephalocele is congenital defects in the sphenoid bone through which meninges and brain tissue have herniated; the defect, located in the midline of the base of the skull, was first reported by Richter in 1813. The nine cases of transsphenoidal meningoencephalocele have been reported. Patients with transsphenoidal meningoencephalocele also may have other midline craniocerebral and midfacial anomalies, including additional meningoencephalocele hypertelorism, cleft palate, and abnormalities...
A Case of Congenital Cystic Adenomatoid Malformation (Type1) of the Lung.
Dong Sik Kim, Hwang Min Kim, Jae Seung Yang, Baek Keun Kim, Jong Soo Kim, Dong Hwan Shin
Clin Exp Pediatr. 1990;33(6):830-834.   Published online June 30, 1990
A rare form of congenital cystic lung disease, characterized by the presence of one or usually multiple interconnecting cyst, is called congenital cystic adenomatoid malformation of the lung. This disease almost invariably presents either in live premature or stillborn infants, and death in those infants bom alive usually occurs within a few hours of birth. Infants with congenital cystic adenomatoid malformation usually have tachypnea,...
Statistical Analysis of Patients in Seoul National University Children's Hospital (1985~1988).
Kyung Mo Kim, Kwang Wook Ko
Clin Exp Pediatr. 1990;33(6):744-753.   Published online June 30, 1990
Statistical analysis of outpatients and inpatients from 1985 to 1988 was assessed with aims to have an overal grasp of patterns and trends of childhood diseases at Seoul National University Children, s Hospital. 1) Number of outpatient visits were totally 458,390 with annual number of visits of 144,754 and average daily number of 461, including 241 visits in Department of Pediatrics. 2) Number of patients at Eemergency...
Preventive Effect of Single Dose Vitamin K for the Late Hemorrhagic Disease of Infancy.
Young Youn Choi, Hwa Il Kwag, Byung Hee Kim, Tai Ju Hwang
Clin Exp Pediatr. 1990;33(5):606-614.   Published online May 31, 1990
To evaluate the preventive effect of single dose vitamin K for the late hemorrhagic disease of infancy, hepaplastin test was carried out in 15 breast-fed and 12 formula-fed babies. Vitamin Ki lmg was injected immediately after the birth intramuscularly and the test was performed the 1st (before vitamin k administration), 3rd, 7th, 28th days of life and the end of the 2nd and...
A case of Second Malignant Neoplasm Complicating Hodgkin's Disease in Remission.
Hong Hoe Koo, Jong Woon Choi, Sang Oh Na, Il Soo Ha, Hee Young Shin, Hyo Seop Ahn, Yeon Lim Suh, Chul Woo Kim, Je Geun Chi
Clin Exp Pediatr. 1990;33(4):564-572.   Published online April 30, 1990
Recent advances in the treatment of cancer have resulted in increased survival and possible cure for many malignant disorders, particularly childhood cancers. There has been a marked improvement in the treatment of childhood Hodgkin’s disease, and five-year survival rates for even advanced stages of Hodgkin’s disease approach or exceed more than 75% with modern treatment policies. However, successful therapy in childhood cancer is frequently...
A clinicostatistical Study of Congenital Intestinal Obstruction.
Min Young Lee, Young Sook Hong, Se Jin Kang, Soon Kyum Kim, Pyung Hwa Choe
Clin Exp Pediatr. 1990;33(4):456-462.   Published online April 30, 1990
A clinicostatistical assessment of the 134 patients with congenital intestinal obstruction who were admitted to the department of pediatrics and pediatric surgery. Korea university medical center from Feb. 1979 to June. 1988 was performed. The results were as follows. 1) Congenital hypertrophic pyloric stenosis (43 cases) was the' most common congenital intestinal obstruc- tion, and congenital megacolon (24 cases), imperforate anus (23 cases), omphalocele (11 cases),...
A Case of Retroperitoneal Lymphangioma.
Gyu Jin Oh, Jin Hyeon Park, Hee Jung Kwon, In Sil Lee, Kui Won Park, Je Geun Chi
Clin Exp Pediatr. 1990;33(3):422-428.   Published online March 31, 1990
Cystic lymphangioma, or cystic hygroma, is a true, benign, congenital multic-ystic tumor arising from sequestration of embryonic lymphatic tissue. Most often it occurs at birth or early in life, and it was found most commonly in the neck, but rarely in the retroperitoneum and its distribution coincides with that of the primitive lymph sac. We have experienced a case of retroperitoneal cystic lymphangioma in...
Cystinurua in Siblings.
Sung Ik Cho, Min Yong Oum, Jae Ock Park, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(3):351-359.   Published online March 31, 1990
We report cystinuria in siblings. Renal colic, hematuria, dysuria and stone passage were developed in younger brother (4 year 6 month old boy). But the elder sister (6 year old girl) had no specific symptoms nor signs. The identification of the disease was proved by cyanide nitroprusside test and amino acid analysis of urine. In our patients the chromatographic amino acid patterns of urine showed...
A Case of Congenital Cysitic Adenomatoid Malformation of Lung.
Youe Kawn Kim, Deuk Hwan Jun, Bae Young Kim, Won Il Park, Kyung Ja Lee
Clin Exp Pediatr. 1990;33(2):225-228.   Published online February 28, 1990
Congenital cystic adenomatoid malformation is a rare variant of pulmonary cystic disease char- acterized by a mass of cysts lined by proliferating bronchial or cuboidal epithelium. The onset of symptoms, which are cyanosis, and tachypnea, usually occurs during the first week of life. We have experienced a case of congenital cystic adenomatoid malformation in a 9 month-old female. The diagnosis was mady by chest...
Immunomodulation Therapy in Children with Aplastic Anemia.
Won Suk Suh, Ki Sik Min, Woo Gun Choi, Hack Ki Kim, Kyoung Sn Lee, Soon Yong Lee
Clin Exp Pediatr. 1990;33(2):170-177.   Published online February 28, 1990
Thirty patients with aplastic anemia(fifteen severe aplastic anemia and fifteen moderate aplastic anemia) treated with antilymphocyte globulin and cyclosporin A as a kind of immunomodulation therapy were studied by analysing hematologic reseponses and complications. The results were as follows; 1) Nineteen out of thirty patients (63.3%) treated with anti lymphocyte globulin plus cyclosporin A showed responses (complete response of 33.3%, partial response of 30.0%). 2) Hematologic responses according...
A Clinical Study of Hereditary Spherocytosis.
Ki Ho Kim, Kun Soo Lee, Haeng Mi Kim, Doo Hong Ahn
Clin Exp Pediatr. 1990;33(1):81-87.   Published online January 31, 1990
The following results were obtained from eight cases of hereditary spherocytosis (HS) who were admitted at the Department of Pediatrics, Kyung-pook National University Hospital from July 1984 to January 1989. The percentage of HS among the pediatric hematology patients during the same period was 2.6%. Male amd female were one and seven respectively. The mean age at the diagnosis and at onset of symptom was...
Clinical Studies on Congenital Heart Diseases.
Hee Young Chun, Dae Churl Chung, In Kyung Sung, Kyong Su Lee, Du Bong Lee
Clin Exp Pediatr. 1990;33(1):66-74.   Published online January 31, 1990
A retrospective study of 10 years* experience with surgical treatment of congenital heart disease in the St. Mary’s Hospital from 1978 to 1987 was made. Data were analyzed on 188 children with congenital heart disease who had received corrective heart surgery under the age of 18 years. The results were as follows: 1) Out of 188 patients, ventricular septal defect(54.2% of all) was the most...
Statistical Analysis of Death Cases in Pediatric Ward.
Kui Ae Jang, Kyeung Bae Park, Jae Ock Park, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(1):1-9.   Published online January 31, 1990
Statistical analysis of death cases during the 9 years from Jan. 1979 to Dec. 1987 in pediatric ward of Soonchunhyang university hospital was carried out. The following results were observed. 1) Total numbers of admission during the 9 years were 16365, of whom 296 expired. 2) Average mortality rate was 1.8% and the annual mortality rate showed decreasing tendency from 1979 to 1987. 3) In age distribution, the neonates...
A Clinicostatistical Study of Congenital Digestive tract Anomalies.
Young Ok Park, Ju Hwi Kim, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1989;32(12):1686-1705.   Published online December 31, 1989
A clinicostatistical review was performed on 151 patients of congenital digestive tract anomalies in infants and children diagnosed and treated at the Department of Pediatrics and Surgery of Kwangju Christian Hospital from January, 1983 to June, 1988. The results are summarized as follows: 1) The most frequently encountered congenital anomaly of the digestive tract was congenital hypertrophic pyloric stenosis with 41 cases(25.9%), followed by obstruction of...
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